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正文 第111章:阿司匹林?(第1页/共3页)

【柳树皮能止疼这件事,几千年前的古巴比伦、古埃及,以及我们中国的老祖先们早就已经察觉了,但其中的关键物质水杨酸,却直到19世纪末才被提取出来】

【将柳树皮捣烂后,榨取出来的汁液会含有水杨苷,也叫柳甘,它是水杨酸和葡萄糖分子的结合物。人体摄入这种物质后,经过消化会分解为水杨酸】

【在上世纪s1赛季和1918年横扫欧洲、杀伤1亿人口的西班牙大流感中,有一种主要成分是水杨酸的药物直接登上神坛,并且和青霉素并称医药史上的三大药物之一,这种药就是阿司匹林】

【严格一点说,阿司匹林的主要成分是乙酰水杨酸,因为水杨酸喝多了很伤肠胃。乙酰水杨酸是化工合成的药物,不仅没有破坏水杨酸的药效,反而将水杨酸的副作用降到了最低,一经面世就迅速登上神坛】

【直到现在,阿司匹林仍然是适用范围最广泛的药物之一,主要用作退热、镇痛、抗炎、抗风湿,还能阻止血栓形成,临床上用于预防短暂脑缺血发作、心肌梗死、人工心脏瓣膜和静脉瘘或其他手术后血栓的形成】

【从柳树汁到水杨苷、水杨酸的故事还和疟疾有关,因为疟疾患者(打摆子)通常会忽冷忽热,在那个分不清症状和病因的年代,通常认为退热了病就自然好了,柳树汁恰好有退热、止痛的功效,真是恰逢其会】

【之后欧洲各界对水杨酸展开了研究,最早的乙酰水杨酸是在一家染坊里合成的.别奇怪,那时的化学工业蓬勃发展,染坊和制药厂之间的界限并不清晰.】

【说回正题,从柳树汁液中提取水杨苷非常简单,取柳树中较为粗壮的柳枝剥皮(白柳、紫柳为佳,树皮内部呈淡红色的药效会更好),将柳树皮洗净切块后浸泡在水中并加热至沸腾,转中火煮60分钟后】

【过滤掉残余的柳树皮,此时一碗红褐色的柳树茶就做好了,轻微的头疼脑热牙疼关节疼,用这碗茶就能缓解】

金陵城,平安医馆中。

每逢天幕亮起的日子,除非是性命攸关或难捱的病症,一般很少有患者登门。

所以每到这个日子,一众大夫、学徒、医馆杂役等人都乐得悠闲,平安医馆中的马大夫、医馆学徒等也是如此。

不过此时几人的脸色是变了又变,最后化为狂喜。

“与青霉素齐名?”饶是见多识广的马大夫也不禁倒吸了口凉气,而且不同于青霉素麻烦、苛刻的制取条件,水杨苷的原料竟是柳树皮的汁液?

一众学徒也被吓到了,反应过来后就抓起纸币,将制备流程抄录下来,并精简文字。

“白、紫柳树皮,熬煮至沸腾,转中火煮半个时辰。”

“柳树枝熬水具有祛风利湿、解毒消肿,民间的药方,煮酒后用来漱口,可治牙齿痛,作浴汤可治痛风身肿发痒。”马大夫说道,这都是他知道的用药经验。

但他行医几十年,年过半百了也没想过,为什么柳树皮汁液具有这样的功效,更加没有想过的是,柳树皮汁液是否还有其他功效。

比如说止痛,除了牙痛,头痛、关节疼痛等症状呢?是否也有效果?

收起汗颜的心思,天幕中还提及了疟疾。柳树皮熬水已经是疟疾牵扯出来的第三种药了(金鸡纳树皮、青蒿素、柳树皮)。

因为亲自试过从苦蒿中提取出来的青蒿素的药效,他对所谓的水杨苷的药效深信不疑。

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